EXOID (TRPS)

EXOID- Particle Size and Zeta Potential Distribution Analyzer

Izon Science, New Zealand brings this revolutionary technology called TRPS or Tunable Resistive Pulse Sensing. This acronym translates to a setup with a size-adjustable or tunable Nanopore across which when a voltage (and pressure) is applied using an electrolyte, momentary resistance in the baseline current occurs with each passing particle. The height and width of resistances in the baseline current across the tunable Nanopore is directly proportional to the size of individual particle and the surface charge.

This technology allows you to use a single, reusable Nanopore to measure Size, Concentration and Zeta Potential of all the particles in your sample thereby greatly reducing analysis time. In addition, the software is uber simple. Reports are detailed and comprehendible.

One can also avail the optional CFR 21 Part 11 compliant software that can implement digital signatures.

SPECIFICATIONS

• Principle– Tunable Resistive Pulse Sensing (TRPS) or impedance-based No lasers or light scattering involved.
• Size tunable pores are used.
• Voltage is applied across a nanopore that is filled with electrolyte, resulting in an ionic current. Particles cross the pore briefly increasing electrical resistance, creating a resistive pulse, which is precisely proportional to particle volume.
• The actual measurement of each particle crossing the pore is achieved through the use of calibration particles that have been accurately calibrated for size and
• Pressure and voltage can be varied in a controlled way which effects the particle velocities enabling the electrophoretic mobility of each particle crossing the
• Applications supported- Size, concentration and zeta potential of exosomes, micro particles, whole blood cells, platelets, liposomes, nano/microbubbles, polymeric drug delivery, particles for immunodetection, viruses, vaccines, bacteria and other nanoparticles within the size range supported.

• The system is portable and compact and can be placed in fume hood or temp controlled
• Hardware comes with an in-built variable pressure module
• Consumables: nanopore membranes and corresponding calibration particles